Gay lawyer Will and straight interior designer Grace share a New York City apartment. Their best friends are gleeful and proud gay Jack and charismatic, filthy-rich, amoral socialite Karen.
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Eric McCormack
Will Truman
Debra Messing
Grace Adler
Megan Mullally
Karen Walker
Sean Hayes
Jack McFarland
Shelley Morrison
Rosario Salazar
Harry Connick Jr.
Leo Markus
Leigh-Allyn Baker
Ellen
Bobby Cannavale
Vince D'Angelo
Tom Gallop
Rob
Leslie Jordan
Beverley Leslie
Tim Bagley
Larry
Blythe Danner
Marilyn Truman
Michael Angarano
Elliot
Brian Jordan Alvarez
Estefan Gloria
Debbie Reynolds
Bobbi Adler
Jerry Levine
Joe
Charles C. Stevenson Jr.
Smitty
Gary Grubbs
Harlin Polk
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